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Mononucleosis and EPO – Is There a Connection?
With all the hype about the use of EPO in cycling in recent years and how injectable EPO in the lab was virtually undetectable until very recently (2003), as well as how the US Anti-Doping Agency , the World Anti-Doping Agency (WADA) and other anti-doping labs around the world suspect that athletes freely use performance-enhancing drugs, namely EPO; some officials are beginning to openly express their frustrations with the shortcomings (underfunding) of the aforementioned agencies.
With recent reports of several athletes contracting mononucleosis, I became curious and decided to do an internet search to see if there was any possibility of a link between EPO and mononucleosis and I found this surprising report (excerpt below).
Author: Paul Schick, MD, Professor Emeritus, Department of Internal Medicine, Thomas Jefferson University Medical College; Research Professor, Department of Internal Medicine, Drexel University College of Medicine:
“Pure aplasia of red blood cells
- Respiratory infections, gastroenteritis, primary atypical pneumonia, infectious mononucleosis, mumps, and viral hepatitis can trigger pure red blood cell aplasia.
- It is important to note that the complication related to EPO seems to be a rare complication considering that approximately 3 million patients are treated with EPO worldwide. Nevertheless, remain aware of the possibility of this complication. In 2002, Casadevall et al recommended that patients receiving EPO be tested for neutralizing anti-EPO antibodies as soon as possible after the onset of unexplained anemia.
- Darbepoetin alfa (Aranesp) was recently introduced and has a different carbohydrate structure than endogenous EPO. Patients receiving this agent should be closely monitored.
- Obviously, the administration of EPO for athletic performance should be avoided. ” http://www.emedicine.com/med/topic1967.htm
“- Medical side effects
EPO generally “thickens” the blood, causing additional circulatory strain as well as damming (clotting) in small blood vessels. The use of EPO is dangerous because it stresses elements of the circulation and quite often is enough to precipitate systemic failures that would otherwise function normally under natural stress levels.”
http://coachsci.sdsu.edu/csa/vol56/fourdrug.htm
“What are the side effects of misusing EPO?
Although the proper use of EPO has enormous therapeutic benefit in the treatment of anemia related to cancer or kidney disease, its misuse can lead to serious health risks for athletes who use this substance simply to gain a competitive advantage. It is well known that EPO, by thickening the blood, leads to an increased risk of several fatal diseases, such as heart disease, stroke, and cerebral or pulmonary embolism. The misuse of recombinant human EPO can also lead to autoimmune diseases with serious health consequences.”
http://www.wada-ama.org/en/dynamic.ch2?pageCategory.id=626
Does this mean that if you have mononucleosis you have used EPO? No, it might go viral, but if you’re an athlete, the US Anti-Doping Agency, World Anti-Doping Agency (WADA) and other anti-doping labs around the world will have their red flags waved for months!
With this information, I became concerned, because if there are tennis players, champions, champions to become or not champions, before they even think of using EPO, they should be aware of the consequences.
Why risk your life for a medal, a cup or a few more dollars? Players and athletes, just say NO and stay away from EPO! Your health and your life are more important to all of us than if you win.
Yours sincerely
Sergio Cruz
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